{ "_id": "6a1ef0b4b401979e7341325b", "Package": "piglet", "Title": "Program for Inferring Immunoglobulin Allele Similarity Clusters\nand Genotypes", "Version": "1.2.0", "Authors@R": "c(person(\"Ayelet\", \"Peres\", role=c(\"aut\",\"cre\"),\nemail=\"ayelet.peres@yale.edu\"),\nperson(\"William\", \"Lees\", role=c(\"aut\"),\nemail=\"william@lees.org.uk\"),\nperson(\"Gur\", \"Yaari\", role=c(\"aut\",\"cph\"),\nemail=\"gur.yaari@yale.edu\"))", "Author": "Ayelet Peres [aut, cre], William Lees [aut], Gur Yaari [aut,\ncph]", "Maintainer": "Ayelet Peres ", "Description": "Improves genotype inference and downstream Adaptive Immune\nReceptor Repertoire Sequence data analysis. Inference of allele\nsimilarity clusters, an alternative naming scheme and genotype\ninference for immunoglobulin heavy chain repertoires. The main\ntools are allele similarity clusters, and allele based\ngenotype. The first tool is designed to reduce the ambiguity\nwithin the immunoglobulin heavy chain V alleles. The ambiguity\nis caused by duplicated or similar alleles which are shared\namong different genes. The second tool is an allele based\ngenotype, that determined the presence of an allele based on a\nthreshold derived from a naive population. 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